Product List in the Nucleoside area :
A. Deoxy Phosphoramidite
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4'-dimethoxytrityl)-2'-deoxythymidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
dT phosphoramidite |
ISN-53A |
98796-51-1 |
|
744.8 |
C40H49N4O8P |
2 |
5'-O-(4,4'-dimethoxytrityl)-N4-Benzoyl-2'-deoxycytidine |
dC Bz |
ISN-30B |
102212-98-6 |
|
833.9 |
C46H52N2O8P |
3 |
5'-O-(4,4'-dimethoxytrityl)-N4-acetyl-2’-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | dC Ac phosphoramidite |
ISN-34B |
154110-40-4 |
|
771.83 |
C41H50N5O8P |
4 |
5'-O-(4,4'-dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | dA Bz phosphoramidite | ISN-41B | 98796-53-3 |
|
857.93 | C47H52N7O7P |
5 |
5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl 2'-deoxyguanosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | dG ibu phosphoramidite | ISN-71B |
93183-15-4 |
|
839.9 | C44H54N7O8P |
6 |
5'-O-(4,4'-dimethoxytrityl) N2-Dimethylaminomethylen-2'-deoxy-guanosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | dG DMF phosphoramidite | ISN-343B | 330628-04-1 |
|
624.69 | C34H36N6O6 |
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4'-dimethoxy)- 2'-O-[(1,1-dimethylethyl)-dimethylsilyl] Uridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | Ribo-U phosphoramidite | ISN-247E | 118362-03-1 |
|
861.04 | C45H61N4O9PSi |
2 |
5'-O-(4,4'-dimethoxy)-N4-acetyl-cytidine-2'-O-[(1,1-dimethylethyl)-dimethylsilyl]- 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | Ribo-C Ac phosphoramidite | ISN-245E | 121058-88-6 |
|
902.09 | C47H64N5P9PSi |
3 |
5'-O-(4,4'-dimethoxy), N6-Benzoyl-Adenosine-2'-O-[(1,1-dimethylethyl) dimethylsilyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | Ribo-A Bz phosphoramidite | ISN-43F | 104992-55-4 |
|
988.19 | C53H66N7O8PSi |
4 |
5'-O-(4,4'-dimethoxy)-N2-isobutyryl Guanosine 2'-O-[1,1-dimethylethyl) dimethylsilyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
Ribo-G ibu phosphoramidite | ISN-55E | 147201-04-5 |
|
970.17 | C50H68N7O9PSi |
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4'-dimethoxytrityl)-2’-O- methyl uridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 2’-OMe-U phosphoramidite | ISN-33B | 110764-79-9 |
|
760.812 | C40H49N4O9P |
2 |
5'-O-(4,4'-dimethoxytrityl)-N4-Acetyl-2’-O- methyl cytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 2’-OMe-C Ac phosphoramidite | ISN-36D | ---- |
|
801.86 | C42H52N5O9P |
3 |
5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2’-O- methyl Adenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 2’-OMe-A Bz phosphoramidite | ISN-42C | 110782-31-5 |
|
887.95 | |
4 |
5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-2’-O- methyl Guanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 2’-OMe-G ibu phosphoramidite | ISN-54D | 150780-67-9 |
|
869.94 | C45H56N7O9P |
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4'-dimethoxytrityl)-2’-Fluoro uridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 2’-Fluoro-U phosphoramidite | ISN-109B | 146954-75-8 |
|
748.77 | C39H46FN4O8P |
2 |
5'-O-(4,4’-dimethoxytrityl)-N4-Acetyl-2’-Fluoro cytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 2’-Fluoro-C Ac phosphoramidite | ISN-110C |
159414-99-0 |
|
789.82 | C41H49FN5O8P |
E. Reverse Abasic phosphoramidite
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
3'-O-(4,4'-dimethoxytrityl)-1’,2’-Dideoxy D-ribose-5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 1’,2’-dideoxy D-ribose phosphoramidite | ISN-473 | 401813-16-9 |
|
620.71 | C35H45N2O6P |
F. Protected deoxy nucleosides
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4’-dimethoxytrityl)-deoxythymidine | dT PNS | ISN-53 | 40615-39-2 |
|
544.6 | |
2 |
5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'-deoxycytidine | dC Bz PNS | ISN-30A | 67219-55-0 |
|
633.7 | C37H35N3O7 |
3 |
5'-O-(4,4'-dimethoxytrityl) N4-Acetyl-2'-deoxycytidine | dC Ac PNS |
ISN-34A |
100898-63-3 |
|
571.62 | C32H33N3O7 |
4 |
5'-O-(4,4'-dimethoxytrityl) N2-isobutyryl-2'-deoxyguanosine | dG ibu PNS | ISN-71A | 68892-41-1 |
|
639.7 | C35H37N5O7 |
5 |
5'-O-(4,4'-dimethoxytrityl)- N2-dimethylaminomethylene-2'-deoxy-guanosine | dG DMF PNS | ISN-343A | 40094-22-2 |
|
824.90 | C43H53N8O7P |
6 |
5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine | dA Bz PNS | ISN-41A | 64325-78-6 |
|
657.7 | C38H35N5O6 |
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4'-dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl] uridine | 2’-OTBDMS-U | ISN-247D | 81246-80-2 |
|
660.82 | C36H44N2O8Si |
2 |
5'-O-(4,4'-dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl] N4-acetyl Cytidine | 2’-OTBDMS-C Ac | ISN-245D | 121058-85-3 |
|
701.88 | C38H47N3O8Si |
3 |
5'-O-(4,4'-dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl] N6- benzoyl Adenosine | 2’-OTBDMS-A Bz | ISN-43E | 104992-55-4 |
|
787.97 | C44H49N5O7Si |
4 |
5'-O-(4,4'-dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl] 2'-O-t-butyldimethylsilyl-N-DMF Guanosine | 2’-OTBDMS-G DMF | ISN-55G | 126922-61-0 |
|
754.94 | C40H50N6O7Si |
5 |
5'-O-(4,4'-dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl] N2-isobutyryl Guanosine | 2’-OTBDMS-G ibu | ISN-55D | 147201-04-5 |
|
769.95 | C41H51N5O8Si |
H. O-Methyl protected nucleosides
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4’-dimethoxytrityl)-2’-O- methyl Uridine | 2’-OMe-U | ISN-33A | 103285-22-9 |
|
560.59 | C31H32N2O8 |
2 |
5'-O-(4,4’-dimethoxytrityl)-N4-Acetyl-2’-O-methyl Cytidine | 2’-OMe-C Ac | ISN-36B | 103285-21-8 |
|
601.64 | C33H35N3O8 |
3 |
5'-O-(4,4’-dimethoxytrityl)-N6-Benzoyl-2’-O-methyl Adenosine | 2’-OMe-A Bz | ISN-42B | 110764-72-2 |
|
687.74 | C39H37N5O7 |
4 |
5'-O-(4,4’-dimethoxytrityl)-N2-isobutyryl-2’-O-methyl Guanosine | 2’-OMe-G ibu | ISN-54C | 114745-26-5 |
|
669.72 | C36H39N5O8 |
I. Protected Fluoro nucleosides
Sr. |
Chemical Name |
Short Name |
ISN |
CAS # |
Structure |
M.Wt |
M.F. |
1 |
5'-O-(4,4’-dimethoxytrityl)-2’-Fluoro Uridine | 2’-Fluoro U | ISN-109A | 146954-74-7 |
|
548.55 | C30H29FN2O7 |
2 |
5'-O-(4,4’-dimethoxytrityl)-N4-Acetyl-2’-Fluoro Cytidine | 2’-Fluoro C Ac | ISN-110B | 159414-98-9 |
|
589.61 | C32H32FN3O7 |
The phosphoramidites of all the above DNA, RNA and Modified Protected Nucleosides can be supplied on custom basis."