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PROCESS
CAPABILITIES - NUCLEOSIDES |
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- Protection
and deprotection
of nucleoside
compounds
-
Transformation
of U to C via
triazolation
process
-
5’-O-Acylations
- Selective
2’-O alkylations
- Fluorination
- Azidation
and catalytic
reduction to
amino derivative
-
Phosphitylation
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PROCESS
CAPABILITIES - NON-NUCLEOSIDES |
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- Side Chain
Photochlorination
(Ar- CH3
to Ar-CH2Cl)
- Cyanation (NaCN,
KCN, CuCN)
- Halogenation
(Aliphatic/Aromatic)
- Reactions
with Phosphorous
Halides
- Catalytic
Hydrogenation 30
Bar; 1500c
- Grignard
reactions
- Friedel-crafts
reaction
- Wittig-
Horner reaction
-
Metal / Ammonia
reduction
-
Boron Chemistry
(Borates,
Boronic Acids,
Boron Mediated
Asymmetric
Synthesis) -
Organometallic
reactions
-
Fries
Rearrangement
-
Oxidations using
Metal Oxides, H2O2,
Per Acids,
Hypochlorite
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Reductions Using
Metal Hydrides,
Nobel Metals,
Ni, Na/ EtOH, Al
Isopropoxide,
Chemical
Reductions
-
Aromatic
Fluorination,
Sulphonation
-
Carbohydrate
Chemistry
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